A Two-Step Synthesis of the “Queen Substance” of the Honey Bee |
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Authors: | Greg W. Ebert |
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Affiliation: | Department of Chemistry , State University of New York College at Buffalo , 1300 Elmwood Avenue, Buffalo, New York, 14222 |
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Abstract: | A synthesis of the “queen substance” was accomplished in two steps from readily available starting materials. The key step was a novel one-pot reduction of 7-oxooctanoic acid to 7-oxooctanal followed by condensation with malonic acid. |
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