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Enantioselective Hydrolysis of 2, 2-Disubstituted Oxiranes Mediated by Microsomal Epoxide Hydrolase |
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| Authors: | Deevi Basavaiah Sarikonda Bhaskar Raju |
| Affiliation: | School of Chemistry , University of Hyderabad , Hyderabad, 500 046, India |
| Abstract: | 2-Aryl-2-methyloxiranes are enantioselectively hydrolyzed with microsomal epoxide hydrolase from pig liver to provide 1, 2-diols containing a tertiary benzylic alcohol stereogenic centre upto 34% enantio-meric purities. |
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