A Convenient One-Step Gingerol Synthesis |
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Authors: | Steven A. Fleming Carrie W. Dyer Julie Eggington |
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Affiliation: | Department of Chemistry and Biochemistry , Brigham Young University , Provo, Utah, 84602 |
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Abstract: | Racemic 6-gingerol can be obtained in a one-pot reaction by hexanal addition to the dianion of zingerone at low temperature. Similarly, addition of octanal or decanal to the dianion provides 8-gingerol or 10-gingerol, respectively. Acid treatment of the gingerols allows for formation of the corresponding shogaols. |
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