An Improved Synthesis of L-Homohistidine |
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Authors: | Janina Altman Meir Wilchek Ralph Lipp Walter Schunack |
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Institution: | 1. Department of Biophysics , Weizmann Institute of Science , Rehovot, Israel;2. Institute of Pharmacy, Free University of Berlin , K?nigin Luise Str. 2+4, D-1000, Berlin (West) |
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Abstract: | Bloemhoff - Kerling's method of L-homohistidine synthesis was modified by employing formamidine acetate in liquid ammonia for imidazole ring formation. The improved procedure significantly shortened the synthetic pathway and resulted in enhanced yield. |
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