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An Efficient Preparation of 7-Methoxychromanone |
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| Authors: | Zhisong Cao Joachim G. Liehr |
| Affiliation: | 1. Department of Pharmacology and Toxicology , University of Texas Medical Branch at Galveston , Galveston, Texas, 77555–1031, USA;2. The Stehlin Foundation for Cancer Research , 1918 Chenevert, Houston, TX, 77003;3. Department of Pharmacology and Toxicology , University of Texas Medical Branch at Galveston , Galveston, Texas, 77555–1031, USA |
| Abstract: | The reaction of m-methoxyphenol 7 with 3-chloropropionaldehyde diethyl acetal 8 and the subsquent treatments gave the corresponding 7-methoxychromanone 6 in overall 54% yield. This method represents an efficient preparation of chromanone. |
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