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A Facile and Practical Procedure for the Synthesis of 8-Hydroxy-4-oxochroman Derivatives
Authors:Tomoyuki Yasunaga  Yoshinori Kato  Shin-ichi Tsukamoto
Institution:1. Chemistry Laboratories, Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd. , 21 Miyukigaoka Tsukuba, Ibaraki , 305 , Japan;2. Chemical Technology Laboratories, Bulk Manufacturing &3. Technology Division, Yamanouchi Pharmaceutical Co., Ltd. , 160-2 Akahama, Takahagi, Ibaraki , 318 , Japan
Abstract:Abstract: Novel 8-hydroxy-4-oxochroman derivatives were prepared from appropriate 4-chromanones via the Baeyer-Villiger oxidation followed by an intramolecular Fries rearrangement.
Keywords:
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