Novel Synthesis of Ethynyl Vinyl Carbinols and 2,5-Disubstituted Furans from Aldehydes |
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Authors: | Zoltan G. Hajos Michael P. Wachter Harvey M. Werblood |
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Affiliation: | R.W. Johnson Pharmaceutical Research Institute at Ortho Pharmaceutical Corporation , Raritan, New Jersey, 08869 |
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Abstract: | Gem-substituted aryl, aralkenyl and 2-furyl ethynyl vinyi carbinols as well as 2,5-disubstituted furans can be obtained by a novel addition and rearrangement reaction of acetylene with the appropriate aldehydes. |
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