Tributyltin Hydride-Induced Free Radical Deoxygenation of the Cyclic Thionocarbonates of Threo-2,3-Dihydroxy Esters and Ketones |
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| Authors: | Ho-Sik Rho |
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| Institution: | 1. Pharmaceutical &2. Health Science Research Institute, Pacific Corporation , Yongin-Si Kyounggi-do, 449-900, Korea |
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| Abstract: | Abstract: A practical and enantiospecific method for the synthesis of optically pure β-hydroxy esters and ketones is described. The key reaction is free radical deoxygenation of the cyclic thionocarbonates of threo-2,3-dihydroxy esters and ketones with tributyltin hydride. |
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