The Chemoselective Cleavage of Acylthioaryltioacetals with Tributyltin Hydride |
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| Authors: | Y Gareau R Zamboni J Y Gauthier M A Bernstein |
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| Institution: | Merck Frosst Centre for Therapeutic Research , P.O. Box 1005 Pointe, Claire-Dorval, Québec, Canada , H9R-4P8 |
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| Abstract: | Acylthioarylthioacetals are cleaved selectively by tributyltin hydride/AIBN affording thioacyls radicals, which can react with tethered carbon-carbon double or triple bond to form functionalized cyclopentanes. |
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| Keywords: | Thymidine adducts Synthesis Characterization |
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