|
|||||
|
|
Deuteration of Non-Stabilized Phosphorus Ylides With DMSO-d6: Convenient Synthesis of Mono-Deuterated Alkenes |
|
| Authors: | Allen B. Reitz Bruce E. Maryanoff |
| Affiliation: | Chemical Research Department , McNeil Pharmaceutical , Spring House, PA, 19477, USA |
| Abstract: | The use of DMSO-d6 as a solvent or cosolvent in the Wittig reaction results in the incorporation of deuterium into the phosphorus ylide and the alkene product. |
| Keywords: | |