The Stereospecific Tert-Butyllithium Reduction of Triene Sulfoxides: Improved Levels of Deuterium Incorporation |
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| Authors: | Gyooson Park William H Okamura |
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| Institution: | Department of Chemistry , University of California , Riverside, California, 92521 |
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| Abstract: | Treatment of triene sulfoxides with t-BuLi and methanol-O-d1 in D2O-wet ether leads to trienes with practical levels (96%) of deuterium incorporation. Alternatively, successive treatment of triene sulfoxides dwith CH3Li and then t-BuLi followed by methanol-O-d1 quench affords similar levels of label incorporation. |
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