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Improved Large-Scale Preparation of 4-Iodopicolinic Acid |
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| Authors: | Olivier Lohse |
| Affiliation: | SANDOZ PHARMA AG, Chemical Process Research and Development Department , CH-4002, Basel, Switzerland |
| Abstract: | Dimethylformamide showed a dramatic catalytic effect in the chlorination of picolinic acid with thionyl chloride. Methyl 4-chloropicolinate was directly transformed to 4-iodopicolinic acid in a good yield. |
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