A Reductive 1,2 Transposition of Acyclic Ketones |
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| Authors: | Gerald L. Larson Lelia M. Fuentes |
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| Affiliation: | Department of Chemistry , University of Puerto Rico Río Piedras , Puerto Rico, 00931 |
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| Abstract: | Earlier we noted that the hydroboration of the trimethylsilyl enol ether of an acyclic ketone results in an elimination of a trimethylsiloxyborane moiety with the subsequent formation of an olefin.1,2 The olefin formed then undergoes hydroboration giving a monoalcohol upon oxidation. (eq 1) We wish to report here on the utility of this sequence, illustrated in eq 1, in the reductive 1,2 transposition of acyclic ketones.3 |
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