Asymmetric Syntheses Vi: Asymmetric Aldol Reaction of D-Camphor Imine Derived From Benzylamine |
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| Authors: | Jiang Yaozhong Liu Guilan Deng Jingen |
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| Institution: | Chengdu Institute of Organic Chemistry , Academia Sinica , Chengdu, P.R. China |
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| Abstract: | Addition of the D-camphor imine of benzylamine to a variety of aldehydes or ketones gives diastereose-lectivities ranging from 16–70%. The d.e. value is attributed by the difference of the orientation of C-11 groups. The rotation of (5e) indicates that addition reaction occurs from the pro-R face of lithium derivative (2). |
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