One-Pot Synthesis of Thiazolidino [3,2-a] Pyrimidine Derivatives |
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| Authors: | Edwige Jeanneau-Nicolle Martine Benoit-Guyod Gérard Leclerc |
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| Affiliation: | Groupe de Pharmacochimie Moléculaire, Laboratoire de Chimie Organique , UFR de Pharmacie - Université Joseph Fourier , (Grenoble I), BP 138, 38240, Meylan-Cedex, France |
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| Abstract: | Reaction of 2-aminothiazoline with an aromatic aldehyde and an activated methylene group (malonitrile, diethylmalonate or ethylcyanoacetate) gave the title compounds. The structures are unambiguously assigned using spectroscopic data and chemical proofs. |
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