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Synthesis of Optically Active Cyanohydrins Using Almond Meal |
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| Authors: | P Zandbergen J van der Linden J Brussee A van der Gen |
| Institution: | Department of Chemistry, Gorlaeus Laboratories , Leiden University , P.O. Box 9502, 2300, RA, Leiden, The Netherlands |
| Abstract: | Asymmetric hydrocyanation of aldehydes was accomplished using almond meal, containing the enzyme oxynitrilase. Optically active cyanohydrins with high levels of enantiomeric purity were obtained following a simple procedure. |
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