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Lewis Acid Mediated Addition of Tri-n-Butylstannylmethylisoxazole with Aldehydes
Authors:Makoto Yamamoto  Kazumi Ohtsuka  Keiki Kishikawa  Shigeo Kohmoto
Affiliation:Department of Materials Science, Faculty of Engineering , Chiba University , 1-33 Yayoi-cho, Inage-ku, Chiba-shi, 263, Japan
Abstract:Lewis acid mediated addition of 5-(tri-n-butylstannyl)methyl-3-methylisoxazole and its analogues with aldehydes have been carried out. Corresponding 5-(β-hydroxy)ethylisoxazoles were obtained in moderate yields, without ring opening of the isoxazole.
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