|
|||||
|
|
Solid-Liquid Phase Transfer Catalysis Without Solvent: Further Improvement in SNAr Reactions |
|
| Authors: | André Loupy Noelle Philippon Philippe Pigeon Jean Sansoulet Hervé Galons |
| Affiliation: | 1. Laboratoire des Réactions Sélectives sur Supports I.C.M.O. , UA 478 du CNRS Université Paris-Sud , B[acaron]timent 410, 91405, ORSAY Cedex, France;2. Laboratoire de Chimie Organique 2 , Faculté de Pharmacie 4 Av. de l'Observatoire , 75270, PARIS Cedex, France |
| Abstract: | Solid-liquid PTC without added solvent efficiently promotes SNAr reactions of a variety of anionic nucleophiles generated in situ. This methodology is applied with success to some examples concerning non-activated aromatic systems. TDA-1 is the most effective catalyst. |
| Keywords: | Phosphaallenes Glycols Aldehydes |