|
|||||
|
|
A Facile and Practical Synthesis of Capsazepine,a Vanilloid Receptor Antagonist |
|
| Authors: | Jeewoo Lee Jiyoun Lee |
| Affiliation: | Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University , Shinlim-Dong, Kwanak-Ku, Seoul, 151-742, Korea |
| Abstract: | A facile and practical synthesis of capsazepine, a vanilloid receptor antagonist, has been accomplished from isovanillin in 8 steps via an efficient intramolecular Mannich cyclization. |
| Keywords: | |