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A Practical Asymmetric Synthesis of A Pseudomonic Acid Precursor from D-Arabinose or D-Xylose |
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| Authors: | Aaron Balog Marvin S. Yu Dennis P. Curran Guixue Yu Daniel R. Carcanague Youe-Kong Shue |
| Affiliation: | 1. Department of Chemistry , University of Pittsburgh , Pittsburgh, Pennsylvania, 15260, USA;2. Cubist Pharmaceuticals , 24 Emily Street, Cambridge, Massachusetts, 02139, USA |
| Abstract: | The asymmetric synthesis of multi-gram quantities of a pseudomonic acid precursor is described. Improvements on the literature synthesis of diacetyl arabinal from arabinose are also reported. |
| Keywords: | |