New Syntheses of Geiparvarin and 2,5-Dimethyl-3(2H)-furanone Via Co2 Mediated Bond Reorganization |
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| Authors: | Y Inoue K Ohuchi S Imaizumi H Hagiwara H Uda |
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| Institution: | 1. Department of Engineering Science , Faculty of Engineering, Tohoku University , Aoba, Sendai, 980, Japan;2. Chemical Research Institute of Non-Aqueous Solutions, Tohoku University , Katahira, Sendai, 980, Japan |
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| Abstract: | A new synthesis of 3(2H)-furanones from 4-hydroxy-2-alkyn-1-one derivatives via CO2 mediated bond reorganization has been developed to the preparation of an antitumor agent, geiparvarin and a constituent of flavors, 2,5-dimethyl-3(2H)-furanone. |
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| Keywords: | Aromatic aldehydes 5 5-Dimethyl-1 3-cyclohexanedione Condensation reaction |
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