First synthesis of Estrogen-Imidazolium Cyclophanes |
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| Authors: | Zhichang Liu Chenghe Zhou Xiaoyu Su Rugang Xie |
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| Institution: | Department of Chemistry , Sichuan University , Chengdu, 610064, P.R. China |
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| Abstract: | A series estrogen-imidazolium cyclophanes have been synthesized for the first time by direct quaternization of 2,4-bis(N-imidazolylmethyl)estrogens and corresponding dibromides in highly diluted acetonitrile solution in excellent yields. All new compounds were characterized by MS, 'HNMR and elemental analysis. |
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| Keywords: | Piperidin-4-one Oxidant Oxime Deoximation |
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