Practically useful Reformatsky Type Reactions of Chlorodifluoroacetate and Bromodifluoroacetate Induced by Samarium(II) Diiodide |
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| Authors: | Masato Yoshida Daiki Suzuki Masahiko Iyoda |
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| Institution: | Department of Chemistry, Faculty of Science , Tokyo Metropolitan University , Hachioji, Tokyo, 192-03, Japan |
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| Abstract: | Treatment of XCF2COOEt (X = Cl and Br) with SmI2 in THF gave efficiently β,β-difluorinated enolate equivalent, which was used for Reformatsky type reaction with aldehydes and ketones to give 2,2-difluoro-3-hydroxy ester. |
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