Studies on the Reactivity of 4-Acetoxy-3-acylamino-2-azetidinones: Stereospecific trans Carbon-Carbon Bond Formation |
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Authors: | Pat Bevilacqua John L Roberts |
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Institution: | Chemical Research Department , Hoffmann-La Roche Inc. , Nutley, NJ, 07110, USA |
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Abstract: | The recent publication of Reuschling and co-workers2 on the synthesis of a carbapenem utilizing, as the key step in the sequence, the stereospecific C-C coupling of 3-substituted-acetoxy-2-azetidinones with cuprates, prompts us to report our related work in this area. |
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