Single Step Syntheses of ω-9-Fluorenylmethyl Esters of Aspartic and Glutamic Acids |
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| Authors: | Peter J Belshaw J Gordon Adamson Gilles A Lajoie |
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| Institution: | Department of Chemistry , University of Waterloo , Waterloo, Ont., Canada , N2L 3G1 |
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| Abstract: | Base lability of the 9-fluorenylmethyl ester makes this group useful in solid phase peptide synthesis when used in combination with the tBoc methodology for preparing cyclic peptides. We describe a simple one step synthesis of the 9-fluorenylmethyl esters of aspartic and glutamic acids. |
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