A Novel Synthesis of 3,4-Discubstituted-1H-pyrazolo[3,4-b]quinolines |
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| Authors: | B Narsaiah A Sivaprasad R V Venkataratnam |
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| Institution: | Indian Institute of Chemical Technology , Hyderabad, 500 007, INDIA |
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| Abstract: | A simple and efficient synthesis of pyrazolo3,4-b] quinolines is described. The synthesis involves reaction of 2-amino-3-cyanoquinoline-4-carboxylates(1) with hydrazine hydrate to give regioselectively only pyrazolo3,4-b]quinolines (2). No formation of pyridazino quinolines (3) is observed. |
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