Improved Nucleophilic Displacements in N-Methyl Pyrrolidinone as a Solvent |
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| Authors: | John Tyman Shoreh Ghorbanian M. Muir Vasiliki Tychopoulous Ian Bruce Ian Fisher |
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| Affiliation: | Department of Chemistry , Brunel University , Uxbridge, Middlesex, UB8 3PH, England |
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| Abstract: | The nucleophilic displacement reactions of 2- and 4- halogenonaphthalic-1,8, anhydrides and the N-imides, of 4,7- dichloroquinolines, the alkylation of lithio alkynes, the methylation of ethyl or methyl diacetylacetate and a variety of related reactions are greatly facilitated in N-methylpyrrolidinone as aprotic solvent. |
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