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Synthesis of 2-Methyl-5-nitroimidazol-1-yl-acetaldehyde |
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| Authors: | L. -X. Yang K. G. Hofer |
| Affiliation: | Institute of Molecular Biophysics, Florida State University , Tallahassee, FL, 32306, U.S.A. |
| Abstract: | Pure 2-methyl-5-nitroimidazol-1-yl-acetaldehyde was synthesized by modified Swern oxidation. This compound can be utilized as reaction intermediate in the synthesis of bioreductive agents (e.g., hypoxic cell radiosensitizers, antibiotics against anaerobic organisms). |
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