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Synthesis of 8-Halopurines by Reaction of Lithiated Purines with Appropriate Halogen Donors |
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| Authors: | Jens MJNols⊘e Lise-Lotte Gundersen Frode Rise |
| Institution: | Department of Chemistry , University of Oslo , P. O. Box 1033, Blinden, Oslo, N-0315, Norway E-mail: l.l.gundersen@kjemi.uio.no |
| Abstract: | Purines lithiated in the 8-position, can be trapped with hexachloroethane, dibromotetrachloroethane, cyanogen bromide and cyanogen iodide, to give a variety of 8-halopurines in excellent yields. |
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