Observations on the Stereochemical Outcome of the UGI Four-Component Condensation |
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| Authors: | Denise M. Flanagan Madeleine M. Joullie |
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| Affiliation: | Department of Chemistry , University of Pennsylvania , Philadelphia, Pennsylvania, 19104-6323 |
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| Abstract: | Investigations were carried out to explain the unexpected distribution of cis and trans products from the Ugi four-component condensation involving a cyclic imine. The nature of the transition state complex was deemed to be a determining factor. The influence of solvent polarity on the isomeric ratio of the products was also examined. |
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