Borohydride Reductions in Dichloromethane: A Convenient,Environmentally Compatible Procedure for the Methylation of Amines |
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| Authors: | Sukanta Bhattacharyya |
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| Institution: | 1. Department of Chemistry , Vijoygarh College , Calcutta, 700032, India;2. Department of Chemistry , University of Mississippi , MS, 38677, USA |
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| Abstract: | The combination of zinc chloride and sodium borohydride in dichloromethane is used to effect reductive aminations of formaldehyde with a variety of primary and secondary amines containing potentially acid-sensitive functional groups in good to excellent yields. |
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