Asymmetric Synthesis XXIII.1 A 100% cis Diastereoselectivity in the SYnthesis of Enantiomerically Pure 2,6-Dialkylpiperidines |
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| Authors: | Emmanuel Theodorakis Jacques Royer Henri-Philippe Husson |
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| Institution: | Institut de Chimie des Substances Naturelles CNRS , 91198, Gif-sur-Yvette, Cedex, France |
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| Abstract: | Enantiomerically pure (+)-(2S,6R)-2-propyl-6-methyl-piperidine 6 has been obtained in 4 steps, 66% overall yield and without separation of diastereomers from the chiral 2-cyano-6-oxazolopiperidine synthon 1c derived from (+)-1,2-diphenyl-2-aminoethanol |
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| Keywords: | Ionic liquids dithiocarbamate synthesis characterization |
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