The Synthesis of Some Naphtho[2,3-b]pyran-5,10-Quinones as Preliminary Models for Biological Evaluations |
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| Authors: | Robin G.F. Giles Ivan R. Green Victor I. Hugo Joanne L. Ireland |
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| Affiliation: | 1. Chemistry Department , Murdoch University , Murdoch , WA , 6150 , Australia;2. Chemistry Department , University of the Western Cape , Private Bag X17, Bellville , 7530 , Republic of South Africa;3. Chemistry Department , Cape Technikon , P.O. Box 652, Cape Town , 8001 , Republic of South Africa |
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| Abstract: | Naphtho[2,3-b]pyran-5,10-quinones related to the known antibiotic, erythrostominone 5, have been synthesized and demonstrate that biological activity is a function of the pyran ring as well as substituents at C-2 and C-4. |
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