|
|||||
|
|
Easy Michael Addition by Solid-Liquid Phase Transfer Catalysis Abnormal Reaction of N-Acetylaminomalonate |
|
| Authors: | G. Bram J. Sansoulet H. Galons M. Miocque |
| Affiliation: | 1. Laboratoire des Réctions Sélectives sur Supports. UA CNRS 478, Université Paris-Sud , B[acaron]t. 410, 91405, Orsay Cedex, France;2. Laboratoire de Chimie Organique Thérapeutique. UA CNRS 496, Faculté de Pharmacie, Av. J. B. Clément , 92296, Ch[acaron]tenay-Malabry Cedex, France |
| Abstract: | Solid-liquid phase transfer catalysis (PTC) without added solvent efficiently promotes Michael addition of substituted malonates on hindered acceptors. A rearrangement of adducts formed by addition of diethyl N-acetylaminomalonate is described. |
| Keywords: | |