Synthesis of 2-Aroylimjnopyrimido[3,2-B]-1,2,4-Thiadiazolines |
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| Authors: | K Kamala P Jayaprasad Rao K Kondal Reddy |
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| Institution: | Department of Chemistry , Osmania University , Hyderabad , 500 007 , India |
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| Abstract: | N-Aroyl-N′-(pyrimid-2-yl)-thioureas (2) have been synthesised by the reaction of 2-amino pyrimidines (1) with aroyl chlorides and ammonium thiocyanate in acetone- Cyclisation of 2 with PCl5 in POCl3 and as well as by oxidising agents gave 2-aroyHrninopyrimido3,2-b]-1,2,4-thiadiazolines (3). |
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