Design and synthesis of trifunctional perfluorophenyl azide-based photoactivatable reagents |
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Authors: | Sui Xiong Cai John F. W. Keana |
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Affiliation: | 1. Acea Pharmaceuticals, Inc., a subsidiary of CoCensys, Inc. , 213 Technology Drive, Irvine, CA, 92715, USA;2. Department of Chemistry , University of Oregon , Eugene, OR, 97403, USA |
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Abstract: | The novel trifunctional perfluorophenyl azide based photoactive compounds 3, 6 (unstable), 10 and 13 are described. Diels-Alder reaction of maleimide 13 with diene-heteropolytungstate 14 produced the PFPA-HPT-maleimide trifunctional conjugate 15. |
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