Ring‐Rearrangement Metathesis |
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Authors: | Nicole Holub Siegfried Blechert Prof. Dr. |
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Affiliation: | Institute of Chemistry, Technische Universit?t Berlin, Stra?e des 17. Juni 135, D‐10623 Berlin, Germany, Fax: (+49)?30‐314‐29745 |
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Abstract: | Ring‐rearrangement metathesis (RRM) refers to the combination of several metathesis transformations into a domino process, in which an endocyclic double bond of a cycloolefin reacts with an exocyclic alkene. RRM has proven to be a powerful method for the rapid construction of complex structures. The extension of the basic ring‐opening–ring‐closing metathesis process by further metathesis steps as well as an examination of the driving forces, limits, scope, recent advantages, and future perspectives of these domino sequences is presented with various examples, thus reflecting the high efficiency and utility of RRM in organic synthesis. |
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Keywords: | catalysis domino reactions metathesis natural‐product synthesis ring rearrangement |
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