The Role of Resveratrol in Human Male Fertility |
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| Authors: | Laura M Mongioì Sarah Perelli Rosita A Condorelli Federica Barbagallo Andrea Crafa Rossella Cannarella Sandro La Vignera Aldo E Calogero |
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| Institution: | Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy; (L.M.M.); (S.P.); (R.A.C.); (F.B.); (A.C.); (R.C.); (S.L.V.) |
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| Abstract: | Resveratrol (RSV) (3,4′,5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer’s disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa. |
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| Keywords: | resveratrol human male fertility sperm parameters cryopreservation |
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