Self-Associating Polymers Chitosan and Hyaluronan for Constructing Composite Membranes as Skin-Wound Dressings Carrying Therapeutics |
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Authors: | Katarína Valachov Ladislav olts |
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Affiliation: | Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, SAS, Dúbravská cesta 9, SK-84104 Bratislava, Slovakia; |
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Abstract: | Chitosan, industrially acquired by the alkaline N-deacetylation of chitin, belongs to β-N-acetyl-glucosamine polymers. Another β-polymer is hyaluronan. Chitosan, a biodegradable, non-toxic, bacteriostatic, and fungistatic biopolymer, has numerous applications in medicine. Hyaluronan, one of the major structural components of the extracellular matrix in vertebrate tissues, is broadly exploited in medicine as well. This review summarizes that these two biopolymers have a mutual impact on skin wound healing as skin wound dressings and carriers of remedies. |
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Keywords: | antioxidants chitin hyaluronic acid l-(+)-ergothioneine MitoQ resveratrol SkQ wound healing |
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