a Laboratoire de Catalyse de Lille associé au CNRS, ENSCL, B.P. 108, 59652 Villeneuve d’Ascq Cedex, France
b PPG-SIPSY, Z.I. La Croix Cadeau, B.P. 79, 49242 Avrillé Cedex, France
Abstract:
Benzoylacetate esters and aryl-substituted derivatives are efficiently reduced in 2-propanol using the readily available catalytic combination (1S,2R)-ephedrine/RuCl2(η6-p-cymene)]2 to give the corresponding alcohols in high yields and enantioselectivities (up to 94% ee).