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Synthesis,characterization and biological activities of <Emphasis Type="Italic">N</Emphasis>-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II)
Authors:Nenad Filipović  Tamara Todorović  Rade Marković  Aleksandar Marinković  Srđan Tufegdžić  Dejan Gođevac  Katarina Anđelković
Institution:(1) Faculty of Agriculture, University of Belgrade, Nemanjina 6, 11081 Belgrade, Republic of Serbia;(2) Faculty of Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Republic of Serbia;(3) Faculty of Technology and Metallurgy, Karnegijeva 4/V, Belgrade, Serbia;(4) Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Njegoševa 12, P.O. Box 815, 11001 Belgrade, Republic of Serbia
Abstract:Condensation derivatives of ethyl hydrazinoacetate with 2-formylpyridine and quinoline-2-carboxaldehyde were synthesized. Pd(II), Pt(II) and Cd(II) complexes with the 2-formylpyridine derivative and a Cd(II) complex with the quinoline-2-carboxaldehyde derivative were synthesized and characterized by spectroscopic techniques. In the complexes, both ligands are coordinated in neutral NN bidentate modes, while the remaining two coordination sites are occupied by chloride. All compounds showed biological activity when tested against Escherichia coli, Bacillus subtilis and Staphylococcus aureus.
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