六～八元瓜环与咪唑[4,5-f]-1',10'-菲咯啉衍生物的相互作用

合成了2-苯基-咪唑[4,5-f]-1',10'-菲咯啉和对二甲氨基-2-苯基-咪唑[4,5-f]-1',10'-菲咯啉两种咪唑[4,5-f]-1',10'-菲咯啉衍生物, 并经过一、二维核磁共振谱以及质谱方法的验证. 利用¹H NMR、质谱以及紫外可见分光光度法, 考察了以六～八元瓜环为主体, 咪唑[4,5-f]-1',10'-菲咯啉衍生物为客体的作用体系, 以及形成的主客体包结配合物的结构特征. 研究结果表明: 三种瓜环均与2-苯基-咪唑[4,5-f]-1',10'-菲咯啉发生相互作用, 客体以较小的苯基一端穿过瓜环内腔直至苯基部分和菲咯啉部分分别露置在瓜环的两个端口外, 特别是八元瓜环能容纳两个客体分子. 而对二甲氨基-2-苯基-咪唑[4,5-f]-1',10'-菲咯啉仅能与七及八元瓜环相互作用, 作用模式与前者相同.

Interaction of Cucurbit[n]urils (n=6～8) with Imidazo[4,5-f]- 1′, 10′-phenanthroline Derivatives

Two imidazo[4,5-f]-1',10'-phenathroline derivatives have been synthesized and characterized by using ¹H NMR technique and mass spectroscopy methods. They are 2-phenylimidazo[4,5-f]-1',10'-phenathroline and 2-(p-dimethylaminophenyl)-2-phenylimidazo[4,5-f]-1',10'-phenathroline. Host-guest interac-tion of cucurbit[n]urils (n＝6～8) with the phenathroline derivatives has been investigated by NMR techniques, mass spectrum and UV absorption methods. The experimental results reveal that phenyl part of the guests penetrates the cavity of cucurbit[n]urils (n＝6～8) while phenyl and phenanthroline parts of the guests are located at the each port of a cucurbituril. Particularly, a cavity of cu-curbit[8]uril accommodates two of the guests.