Structural determination of three new eudesmanolides from Inula helenium |
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| Authors: | Ma Xiao-Chi Liu Ke-Xin Zhang Bao-Jing Xin Xiu-Lan Huang Jian |
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| Institution: | School of Pharmaceutical Sciences, Dalian Medical University, Dalian 116027, PR China. maxc1978@sohu.com |
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| Abstract: | Ten sesquiterpenens were isolated from Inula helenium. Among them, three eudesmanolides: 15-hydroxy-11betaH-eudesm-4-en-8beta,12-olide (1), 3alpha-hydroxy-11betaH-eudesm-5-en-8beta,12-olide (2) and 2beta, 11alpha-dihydroxy-eudesm-5-en-8beta,12-olide (3) are new compounds. Their chemical structures were determined by spectral methods including 2D NMR. |
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| Keywords: | NMR 1H NMR 13C NMR 2D NMR Inula helenium eudesmanolides sesquiterpene lactones |
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