An evaluation of hofmann and cope elimination routes to (±)-2-n-propylthietane

A synthetic route to (±)-2-n-propylthietane 1 that utilises a silver oxide-induced Hofmann elimination is described together with an evaluation of the potential of a Cope elimination as an alternative and more cost-effective route to 1 . Some chemistry of the isomeric intermediate thiete sulfones 5 and 12 from each of these respective eliminations is presented.