Alkylation of quinazoline-2,4(1H,3H)-diones with 1,4-dibromo-2-methylbut-2-ene under phase-transfer-catalysis |
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| Authors: | Johannes Reisch Marlies Iding Cyril Odianose Usifoh |
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| Abstract: | Quinazoline-2,4(1H,3H)-dione ( 1 ) was reacted with 1,4-dibromo-2-methylbut-2-ene ( 2 ) to give two dialkylated products and two monoalkylated products. The reaction of 6,7-dimethoxyquinazoline-2,4(1H,3H)-dione ( 8 ) with 1,4-dibromo-2-methylbut-2-ene ( 2 ) resulted in the formation of three dialkylated products. |
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