On the orientation in lithiation and bromination of dithieno[3,4-b:3′,2′-d]pyridine

The 3-position of dithieno3,4-b:3′,2′-d]pyridine was found to be most reactive with regard to lithiation, bromination and halogen-metal exchange. The lithium compounds were trapped as the formyl derivatives by reaction with N,N-dimethylformamide.