Studies on pyrrolidinones. Synthesis of 2-(5-oxo-2-pyrrolidinyl)-1,3,4-oxadiazoles and 2-(5-oxo-2-pyrrolidinyl)benzimidazoles |
| |
Authors: | Pascal Cauliez Daniel Couturier Benoît Rigo Dominique Fasseur Patrice Halama |
| |
Abstract: | The condensation of pyroglutamic acids with 1,2-phenylenediamine leads to 2-(5-oxo-2-pyrrolidinyl)benzimidazoles and the cyclization of disilylated diacylhydrazines derived from the same acids gives 2-(5-oxo-2-pyrrolidinyl)-1,3,4-oxadiazoles. These compounds show weak antifungal activity. |
| |
Keywords: | |
|
|