Reaction of 1-formyladamantane with heterocyclic compounds. Mass spectra,antibacterial and antifungal activity |
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Authors: | G. Fenech P. Monforte A. Chimirri S. Grasso |
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Abstract: | 1-Formyladamantane reacts with some amino derivatives to give I, II, III and IV. 3-Substiluted 2-adamantyl-4-thiazolidinones (V), (VI) and (VII) were obtained by reacting the above compounds with mercaptoacetic acid. Their structure was established by ir, pmr and mass spectroscopy. All compounds synthesized inhibit the growth of gram-negative and gram-positive bacteria and fungi. |
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