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The assay of antibiotics in pharmaceutical preparations using reverse-phase HPLC
Authors:Kay R. Bagon
Abstract:Chromatographic methods are presented for the determination of chloramphenicol, erythromycin, tyrothricin, nystatin, penicillin, streptomycin, sulphanilamides and nitrofurans, in some pharmaceutical formulations. The methods have been applied in routine analysis and are in general capable of distinguishing the main antibiotic from decomposition products and likely congeners.
Keywords:Liquid chromatography, HPLC  Reverse phase separation of 9 antibiotics  Down to 5 min analysis time, less than 4% repeat variation  Precise analytical conditions given
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