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A method for the determination of some organophosphorus insecticides in human serum
Authors:M. De Potter  R. Muller  J. Willems
Affiliation:(1) Laboratory of Medical Toxicology, Technical Division of the Army, Vilvoorde;(2) J. F. and C. Heymans Institute of Pharmacology, University of Ghent Medical School, De Pintelaan 135, B-9000 Ghent, Belgium;(3) Present address: Laboratory of Organic Chemistry, State University of Ghent, Krijgslaan 271-S4, B-9000 Ghent, Belgium;(4) Present address: Department of Organic Chemistry, State University of Mons, B-7000 Mons, Belgium
Abstract:Summary A simple and rapid method for the determination of organophosphorus insecticides in serum of poisoned patients is described. The compounds are extracted with benzene and the extraction residue is gas chromatographed on a glass capillary column with alkali flame ionisation detection. Concentrations from 2 ng cm−3 can be determined. As an example, results of the analysis of serum samples of three patients, poisoned with parathion and methylparation, are given.
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